Alaska Airlines flight AS 4581: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Mon-Sat 06:15 Saint Louis (STL) 1 08:22 Los Angeles (LAX)
AS 4581 Non-stop Airbus A319 (319) 4:07 Valid until 2025-05-03
Codeshare flight, operated by American Airlines.(AA 1854)
Sun 06:15 Saint Louis (STL) 1 08:22 Los Angeles (LAX)
AS 4581 Non-stop Airbus A319 (319) 4:07 Operates only on 2025-05-04
Codeshare flight, operated by American Airlines.(AA 1854)
Daily 07:05 Fayetteville/Springdale (XNA) 08:58 Chicago O'Hare (ORD) 3
AS 4581 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:53 Effective 2025-05-05 through 2025-05-14
Codeshare flight, operated by American Airlines.(AA 3930)
Daily 08:50 Los Angeles (LAX) 12:13 Denver (DEN)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:23 Effective 2025-05-15 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 6196)
Daily 12:43 Denver (DEN) 14:21 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:38 Effective 2025-09-08 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 6524)
Daily 13:00 Denver (DEN) 14:44 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:44 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 6524)
Daily 13:00 Denver (DEN) 14:56 Los Angeles (LAX)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:56 Effective from 2026-02-12
Codeshare flight, operated by American Airlines.(AA 6524)
Daily 16:41 Indianapolis (IND) 18:10 Dallas Fort Worth (DFW)
AS 4581 Non-stop Airbus A321 (321) 2:29 Effective 2025-10-26 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 3034)
Daily 20:14 Chicago O'Hare (ORD) 3 21:21 Milwaukee (MKE)
AS 4581 Non-stop Canadair CRJ 700 (CR7) 1:07 Effective 2025-06-05 through 2025-07-03
Codeshare flight, operated by American Airlines.(AA 6432)
Daily 20:20 Phoenix Sky Harbor (PHX) 4 22:48 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2025-08-06 through 2025-08-19
Codeshare flight, operated by American Airlines.(AA 6373)
Daily 20:20 Phoenix Sky Harbor (PHX) 4 22:48 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2025-08-21 through 2025-08-29
Codeshare flight, operated by American Airlines.(AA 6373)
Mon,Tue,Sun 20:20 Phoenix Sky Harbor (PHX) 4 22:48 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2025-08-31 through 2025-09-02
Codeshare flight, operated by American Airlines.(AA 6373)
Daily 20:20 Phoenix Sky Harbor (PHX) 4 22:57 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2025-10-06 through 2025-10-25
Codeshare flight, operated by American Airlines.(AA 6373)
Daily 20:37 Phoenix Sky Harbor (PHX) 4 23:06 Medford (MFR)
AS 4581 Non-stop Embraer EMB 175 (E75) 2:29 Effective 2025-07-06 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 6373)
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This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 4581: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4581
06:15
Saint Louis (STL) 1

08:22
Los Angeles (LAX)
Valid until 2025-05-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 1854)
Duration: 4:07, non-stop
Airbus A319 (319)
Alaska Airlines AS4581
06:15
Saint Louis (STL) 1

08:22
Los Angeles (LAX)
Operates only on 2025-05-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 1854)
Duration: 4:07, non-stop
Airbus A319 (319)
Alaska Airlines AS4581
07:05
Fayetteville/Springdale (XNA)

08:58
Chicago O'Hare (ORD) 3
Effective 2025-05-05 through 2025-05-14
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3930)
Duration: 1:53, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4581
08:50
Los Angeles (LAX)

12:13
Denver (DEN)
Effective 2025-05-15 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6196)
Duration: 2:23, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
12:43
Denver (DEN)

14:21
Los Angeles (LAX)
Effective 2025-09-08 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6524)
Duration: 2:38, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
13:00
Denver (DEN)

14:44
Los Angeles (LAX)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6524)
Duration: 2:44, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
13:00
Denver (DEN)

14:56
Los Angeles (LAX)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6524)
Duration: 2:56, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
16:41
Indianapolis (IND)

18:10
Dallas Fort Worth (DFW)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3034)
Duration: 2:29, non-stop
Airbus A321 (321)
Alaska Airlines AS4581
20:14
Chicago O'Hare (ORD) 3

21:21
Milwaukee (MKE)
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6432)
Duration: 1:07, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4581
20:20
Phoenix Sky Harbor (PHX) 4

22:48
Medford (MFR)
Effective 2025-08-06 through 2025-08-19
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:28, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
20:20
Phoenix Sky Harbor (PHX) 4

22:48
Medford (MFR)
Effective 2025-08-21 through 2025-08-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:28, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
20:20
Phoenix Sky Harbor (PHX) 4

22:48
Medford (MFR)
Effective 2025-08-31 through 2025-09-02
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:28, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
20:20
Phoenix Sky Harbor (PHX) 4

22:57
Medford (MFR)
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4581
20:37
Phoenix Sky Harbor (PHX) 4

23:06
Medford (MFR)
Effective 2025-07-06 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6373)
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Milwaukee (MKE)
  • Fayetteville/Springdale (XNA) - Chicago O'Hare (ORD)
  • Indianapolis (IND) - Dallas Fort Worth (DFW)
  • Los Angeles (LAX) - Denver (DEN)
  • Phoenix Sky Harbor (PHX) - Medford (MFR)
  • Saint Louis (STL) - Los Angeles (LAX)
All Alaska Airlines flights
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